U.S. stock index futures slipped lower Thursday, retreating after disappointing guidance from chipmaker Micron and ahead of the release of key economic data.

At 06:00 ET (10:00 GMT), Dow Jones Futures fell 50 points, or 0.2%, S&P 500 Futures dropped 7 points, or 0.1%, while Nasdaq 100 Futures fell 25 points, or 0.1%. 

Wall Street indexes ended marginally higher on Wednesday, buoyed by Amazon (NASDAQ:AMZN) crossing the $2 trillion valuation mark after it announced a major foray into generative AI.

Investors appear to be in something of a holding pattern ahead of key U.S. inflation data and the upcoming Presidential debate.

Thursday sees the release of the latest reading of weekly jobless claims, durable goods orders, pending home sales, as well as the final reading of the first quarter GDP.

However, most eyes will be on Friday's PCE price index, as this is widely regarded as the Federal Reserve’s preferred inflation gauge.