U.S. stock index futures drifted lower Wednesday in a lukewarm reaction to the U.S.-China trade framework, as investors awaited the release of crucial inflation data. 

At 05:40 ET (09:40 GMT), Dow Jones Futures fell 50 points, or 0.1%, S&P 500 Futures dropped 7 points, or 0.1%, and Nasdaq 100 Futures slipped 35 points, or 0.2%.

The main averages on Wall Street ended higher on Tuesday, spurred on by a jump in shares in electric car manufacturer Tesla (NASDAQ:TSLA).

The tech-heavy NASDAQ Composite gained 0.6%, the blue chip Dow Jones Industrial Average rose 0.3%, and the broad-based S&P 500 gained around 0.6%, posting a third straight positive session to trade less than 2% off the high it notched in February.